Home nocturnal haemodialysis is designed as a simple and practical extended
therapy option for patients.
Duration matters, even with more frequent therapy:
- Improved survival
- Performing more frequent nocturnal haemodialysis has shown similar 5-year survivability rates as deceased donor transplantation.1
- Better cardiovascular outcomes
- More frequent haemodialysis is associated with less dialysis-induced cardiac injury.2
- Improved phosphorus control and middle molecule clearance
- Compared to conventional thrice-weekly in-centre haemodialysis, nocturnal haemodialysis is associated with improved control of hyperphosphatemia, in addition to significantly higher total cleared volume both in phosphorus and β2 microglobulin.3,4
- Improved energy and vitality
- More frequent dialysis, during the day or overnight, may provide significant and wide-reaching therapeutic benefits.
- Quicker time to post-dialysis recovery5,6
- Less dietary restriction7
- Better blood pressure control with fewer antihypertensive medications8,9
Risks and Responsibilities
Despite the health benefits that home and more frequent hemodialysis may provide to those with chronic kidney disease, these forms of therapy are not for everyone. Home hemodialysis with the NxStage System One requires a patient and partner who are committed to being trained on and following the guidelines for proper system operation.
The reported benefits of home hemodialysis may not be experienced by all patients.
The NxStage System One is a prescription device and, like all medical devices, involves some risks. The risks associated with hemodialysis treatments in any environment include, but are not limited to, high blood pressure, fluid overload, low blood pressure, heart-related issues, and vascular access complications. When vascular access is exposed to more frequent use, infection of the site, and other access related complications may also be potential risks. The medical devices used in hemodialysis therapies may add additional risks including air entering the bloodstream, and blood loss due to clotting or accidental disconnection of the blood tubing set.
Certain risks are unique to the home. Treatments at home are done without the presence of medical personnel and on-site technical support. Patients and their partners must be trained on what to do and how to get medical or technical help if needed.
Certain risks associated with hemodialysis treatment are increased when performing nocturnal therapy due to the length of treatment time and because therapy is performed while the patient and care partner are sleeping. These risks include, but are not limited to, blood access disconnects and blood loss during sleep, blood clotting due to slower blood flow or increased treatment time or both, and delayed response to alarms when waking from sleep.
Patients should consult their doctor to understand the risks and responsibilities of performing these therapies using the NxStage System.